1798310-55-0

A selective FFAR3 (GPR41) agonist.

Greater than 94%

N-(2,5-dichlorophenyl)-4-(2-furanyl)-1,4,5,6,7,8-hexahydro-2-methyl-5-oxo-3-quinolinecarboxamide

Biochemical, Chemical, Agonist

C₂₁H₁₈Cl₂N₂O₃

417.3

Crystalline solid

Soluble in organic solvents such as DMSO and dimethyl formamide, which should be purged with an inert gas. The solubility of AR420626 in these solvents is approximately 5 and 2 mg/ml, respectively.

212, 262, 358 nm

ClC1=CC(NC(C2=C(C)NC(CCCC3=O)=C3C2C4=CC=CO4)=O)=C(Cl)C=C1

1S/C21H18Cl2N2O3/c1-11-18(21(27)25-15-10-12(22)7-8-13(15)23)20(17-6-3-9-28-17)19-14(24-11)4-2-5-16(19)26/h3,6-10,20,24H,2,4-5H2,1H3,(H,25,27)

GGTYQECCGLBHGS-UHFFFAOYSA-N

Store at -20°C.

24 months

SDS

AR420626 is supplied as a crystalline solid. A stock solution may be made by dissolving the AR420626 in the solvent of choice. AR420626 is soluble in organic solvents such as DMSO and dimethyl formamide, which should be purged with an inert gas. The solubility of AR420626 in these solvents is approximately 5 and 2 mg/ml, respectively. AR420626 is sparingly soluble in aqueous buffers. For maximum solubility in aqueous buffers, AR420626 should first be dissolved in DMSO and then diluted with the aqueous buffer of choice. AR420626 has a solubility of approximately 0.2 mg/ml in a 1:4 solution of DMSO:PBS (pH 7.2) using this method. We do not recommend storing the aqueous solution for more than one day.

For research use only.Available for shipment within the USA only

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