6902-77-8

upregulates nnos (neuronal nitric oxide synthase/nos i) and decreases acute inflammation through inhibition of lps-induced nf-kappab activity, suppresses the tumor promoting function of ucp2 in a cellular model of warburg effect, produces blue colored pigments by binding to amino acids, inhibits toll-like receptor (tlr) signaling and the production of pro-inflammatory cytokines, preventing sepsis and increasing survival in animal models of infection, increases glucose-stimulated insulin secretion, mitochondrial membrane potential and atp levels in pancreatic island cells, increases bax/bcl-2 ratio and induces parp cleavage and caspase-3- and caspase-9-mediated apoptosis in non-small cell lung cancer (nsclc) cells, chemical promoter of epstein-barr virus (ebv) lytic cycle activation and suppressor of ebv infection, cell permeable inhibitor of uncoupling protein 2 (ucp2), sensitizes multidrug-resistant cancer cells to cytotoxic agents through ucp2 inhibition, inhibits nlrp3 and nlrc4 inflammasome activation via autophagy suppression, anticancer, antimetastatic and anti-angiogenic agent, anti-inflammatory agent.

Greater than 98% by HPLC

Genipin, (+)-Genipin, Methyl (1S,2R,6S)-2-hydroxy-9-(hydroxymethyl)-3-oxabicyclo[4.3.0]nona-4,8-diene-5-carboxylate

Biochemical, Chemical

C₁₁H₁₄O₅

226.2

White to off-white solid.

Soluble in DMSO (50mg/ml), ethanol (5mg/ml), methanol or acetone. Slightly soluble in water.

[H][C@]12CC=C(CO)[C@@]1([H])[C@H](O)OC=C2C(=O)OC

InChI=1S/C11H14O5/c1-15-10(13)8-5-16-11(14)9-6(4-12)2-3-7(8)9/h2,5,7,9,11-12,14H,3-4H2,1H3/t7-,9-,11-/m1/s1

AZKVWQKMDGGDSV-BCMRRPTOSA-N

Store at -20°C for up to 2 years. Protect from light. Protect from moisture.

SDS

For research use only.Available for shipment within the USA only

This Biochemical carries the LSBio 100% Guarantee