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寿命/PathPlus™ GPER1/GPR30抗体胞外域多克隆ELISA,IHC LS-A4268/50µ;g(1毫克/毫升)/LS-A4268-50
寿命/PathPlus™ GPER1/GPR30抗体胞外域多克隆ELISA,IHC LS-A4268/50µ;g(1毫克/毫升)/LS-A4268-50
商品编号:
LS-A4268-50
品牌:
lsbio
市场价:
¥8500.00
美元价:
5100.00
产品分类:
抗过氧化物酶
公司分类:
Anti_Peroxidase
联系Q Q:
3392242852
电话号码:
4000-520-616
电子邮箱:
info@ebiomall.com
商品介绍
Description
G-proteincoupledestrogenreceptor1(GPER1)promotesneuritogenesisindevelopinghippocampalneurons.ItplaysaroleinacuteneuroprotectionagainstNMDA-inducedexcitotoxicneuronaldeathandincreasesfiringactivityandintracellularcalciumoscillationsinluteinizinghormone-releasinghormone(LHRH)neurons.GPER1inhibitsmatureADIpocytedifferentiationandlipidaccumulation,andisinvolvedintherecruitmentofbeta-arrestin2ARRB2attheplasmamembraneinepithelialcells.Italsofunctionsasareceptorforaldosterone,mediatingrapidregulationofvascularcontractibilitythroughthePI3K/ERKsignalingpathway.Finally,itisimplicatedincancerprogression.TheUniProtConsortium.NucleicAcidsRes.47:D506-515(2019);NucleicAcidsRes.2016Jan4;44(D1):D733-45,PMID:26553804
Target
HumanGPER1/GPR30
SeeAllGPER1/GPR30Antibodies
Host
Rabbit
Reactivity
Human(testedor100%immunogensequenceidentity)
Predicted
Monkey(atleast90%immunogensequenceidentity)
Clonality
Polyclonal
Conjugations
Unconjugated.AlsoavailableconjugatedwithAP,APC,Biotin,FITC,HRP,PE.
Purification
Immunoaffinitypurified
Modifications
Unmodified
Applications
- IHC
- IHC-Paraffin(5-7.5µg/ml)
- ELISA
- Applicationstestedforthebaseformofthisproductonly
PerformingIHC?SeeourcompletelineofImmunohistochemistryReagentsincludingantigenretrievalsolutions,blockingagentsABCDetectionKitsandpolymers,biotinylatedsecondaryantibodies,substratesandmore. |
Immunogen
Synthetic15aminoacidpeptidefrom2ndextracellulardomainofhumanGPR30.PercentidentitywithotherspeciesbyBLASTanalysis:Human,Gorilla,Monkey(100%);Marmoset,Elephant(93%);Mouse,Rat,Hamster,Panda,Horse,Opossum,Platypus(87%);Dog,Bovine,Turkey,Zebrafinch,Chicken(80%).
BlockingPeptide
LS-E28930-Liquid-50µg-$145.00ImmunizingpeptideusedtogenerateLS-A4268.Usefulforpre-absorptionandneutralizationoftheantibody'santigenbindingsite.
Epitope
ExtracellularDomain
Specificity
HumanGPR30.BLASTanalysisofthepeptideimmunogenshowednohomologywithotherhumanproteins.
Presentation
PBS,0.1%SodiumAzide
Storage
Aliquotandstoreundilutedat-20°Corbelowforupto1year.Canbestoredundilutedat4°Cforupto1month.Avoidfreeze-thawcycles.
Restrictions
Forresearchuseonly.
Guarantee
ThisantibodycarriestheLSBIo100%Guarantee.
LSBioGuaranteeAboutGPER1/GPR30
Q99527NM_001505NP_001496.1
品牌介绍
LifeSpan成立于1995年, 主要提供免疫病理产品,如抗体特别是药靶蛋白抗体、蛋白定位、免疫组化相关产品如软件、组织等。公司目前提供近代史万种抗体和产品,为世界各地科学家提供各种优质的产品!抗体产品效价高,效果好!详细资料请登陆LifeSpan inc