寿命/PathPlus™ EDNRB/内皮素B受体抗体N端多克隆IHC LS-A56/50µ；g（1毫克/毫升）/LS-A56-50-免疫在线蚂蚁淘旗下平台

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商品详细寿命/PathPlus™ EDNRB/内皮素B受体抗体N端多克隆IHC LS-A56/50µ；g（1毫克/毫升）/LS-A56-50

寿命/PathPlus™ EDNRB/内皮素B受体抗体N端多克隆IHC LS-A56/50µ；g（1毫克/毫升）/LS-A56-50

商品编号： LS-A56-50

品牌： lsbio

市场价： ¥8500.00

美元价： 5100.00

产地：美国(厂家直采)

公司：

产品分类：抗绵羊

公司分类： Anti_sheep

联系Q Q： 3392242852

电话号码： 4000-520-616

电子邮箱： info@ebiomall.com

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商品介绍

Specifications

Description

EndothelinreceptortypeB(EDNRB)isexpressedinmosttissues.MutationsinthisreceptorareresponsIBLeforHirschsprungdiseasetype2,amultigenicdisorderwithphenotypessuchasbicoloredirides,megacolon,hypopigmentation,andhearingloss.EDNRBhassimilaraffinityforallthreeendothelinsandactivatesaphosphatidylinositol-calciumsecondmessengersystem.Asplicevariant,termedSVR,hasbeendescribed;thesequenceoftheETB-SVRreceptorisidenticaltoET-Breceptor,withtheexceptionoftheintracellularC-terminaldomain.WhilebothsplicevariantsbindendothelinET1,theyexhibitdifferentresponses,whichsuggeststhattheymaybefunctionallydistinct.TheUniProtConsortium.NucleicAcidsRes.47:D506-515(2019);NucleicAcidsRes.2016Jan4;44(D1):D733-45,PMID:26553804

Target

HumanEDNRB/EndothelinBReceptor

SeeAllEDNRB/EndothelinBReceptorAntibodies

Host

Rabbit

Reactivity

Human,Monkey(testedor100%immunogensequenceidentity)

Clonality

Polyclonal

Conjugations

Unconjugated.AlsoavailableconjugatedwithAP,APC,Biotin,FITC,HRP,PE.

Purification

Immunoaffinitypurified

Modifications

Unmodified

Applications

IHC
IHC-Paraffin(4µg/ml)
Applicationstestedforthebaseformofthisproductonly

PerformingIHC?SeeourcompletelineofImmunohistochemistryReagentsincludingantigenretrievalsolutions,blockingagentsABCDetectionKitsandpolymers,biotinylatedsecondaryantibodies,substratesandmore.

Immunogen

Synthetic17aminoacidpeptidefromN-TerminusextracellulardomainofhumanEDNRB.PercentidentitywithotherspeciesbyBLASTanalysis:Human,Gorilla,Monkey(100%);Gibbon(94%);Dog(88%);Marmoset,Goat,Bovine(82%).

BlockingPeptide

LS-E29082-Liquid-50µg-$145.00ImmunizingpeptideusedtogenerateLS-A56.Usefulforpre-absorptionandneutralizationoftheantibody'santigenbindingsite.

Epitope

N-Terminus

Specificity

HumanEDNRB.BLASTanalysisofthepeptideimmunogenshowednohomologywithotherhumanproteins.

Presentation

PBS,0.1%SodiumAzide

Storage

Aliquotandstoreundilutedat-20°Corbelowforupto1year.Canbestoredundilutedat4°Cforupto1month.Avoidfreeze-thawcycles.

Restrictions

Forresearchuseonly.