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Lifespan/PathPlus™ GLP1R / GLP‑1 Receptor Antibody N‑Terminus Polyclonal IF,IHC,WB LS‑A1205/50 µg (1 mg/ml)/LS-A1205-50
Lifespan/PathPlus™ GLP1R / GLP‑1 Receptor Antibody N‑Terminus Polyclonal IF,IHC,WB LS‑A1205/50 µg (1 mg/ml)/LS-A1205-50
商品编号:
LS-A1205-50
品牌:
lsbio
市场价:
¥8500.00
美元价:
5100.00
产品分类:
抗山羊
公司分类:
Goat_resistance
联系Q Q:
3392242852
电话号码:
4000-520-616
电子邮箱:
info@ebiomall.com
商品介绍
Description
Glucagon-likepeptide1receptor(GLP1R)isareceptorforglucagonandglucagon-likepeptide-1(GLP1).Itisinvolvedininsulinsynthesisandrelease,bloodglucosehomeostasis,appetitecontrol,memoryandlearning,aswellascontrolofbreathingandheartrate.StimulationofGLP1Rbyendogenoushormoneinducesmultiplecomplementarymechanisms,whichtogetherresultinaloweringofcirculatingbloodglucoselevels.DesensitizationofGLP1Ronpancreaticbeta-cellsisoneofthecausesofnoninsulin-dependentdiabetesmellitus(NIDDM).Inimmunohistochemistry,GLP1Rhashighestmembranouspositivityonpancreaticbetacells,itisexpressedonneuronsinthebrainandnervoussystem,anditisalsofoundinthestomach,salivarygland,heartmuscle,gallbladder,salivarygland,duodenumandatlowlevelsinafewothertissues.TheUniProtConsortium.NucleicAcidsRes.47:D506-515(2019);NucleicAcidsRes.2016Jan4;44(D1):D733-45,PMID:26553804
(8)Publication(s)
Target
HumanGLP1R/GLP-1Receptor
SeeAllGLP1R/GLP-1ReceptorAntibodies
Host
Rabbit
Reactivity
Human,Mouse(testedor100%immunogensequenceidentity)
Clonality
Polyclonal
Conjugations
Unconjugated.AlsoavailableconjugatedwithAP,APC,Biotin,FITC,HRP,PE.
Purification
Immunoaffinitypurified
Modifications
Unmodified
Applications
- IHC
- IHC-Paraffin(15-20µg/ml)
- Immunofluorescence
- Westernblot
- Applicationstestedforthebaseformofthisproductonly
PerformingIHC?SeeourcompletelineofImmunohistochemistryReagentsincludingantigenretrievalsolutions,blockingagentsABCDetectionKitsandpolymers,biotinylatedsecondaryantibodies,substratesandmore. |
Immunogen
Synthetic16aminoacidpeptidefromN-TerminusextracellulardomainofhumanGLP1R.PercentidentitywithotherspeciesbyBLASTanalysis:Human,Gorilla,Gibbon,Monkey(100%);Mouse,Bovine,Hamster,Elephant,Rabbit,Pig(94%);Rat,Dog,Bat,Panda(88%).
BlockingPeptide
LS-E35682-Liquid-50µg1mg/ml-$145.00ImmunizingpeptideusedtogenerateLS-A1205.Usefulforpre-absorptionandneutralizationoftheantibody'santigenbindingsite.
Epitope
N-Terminus
Specificity
HumanGLP1R.BLASTanalysisofthepeptideimmunogenshowednohomologywithotherhumanproteins,exceptRUSC2(44%).
Presentation
PBS,0.1%SodiumAzide
Storage
Aliquotandstoreundilutedat-20°Corbelowforupto1year.Canbestoredundilutedat4°Cforupto1month.Avoidfreeze-thawcycles.
Restrictions
Forresearchuseonly.
Guarantee
ThisantibodycarriestheLSBIo100%Guarantee.
LSBioGuaranteeAboutGLP1R/GLP-1Receptor
P43220NM_002062NP_002053.3
品牌介绍
LifeSpan成立于1995年, 主要提供免疫病理产品,如抗体特别是药靶蛋白抗体、蛋白定位、免疫组化相关产品如软件、组织等。公司目前提供近代史万种抗体和产品,为世界各地科学家提供各种优质的产品!抗体产品效价高,效果好!详细资料请登陆LifeSpan inc