寿命/PathPlus™ HRH4/组胺H4受体抗体胞质域多克隆IHC LS-A6816/50µ；g（0.7 mg/ml）/LS-A6816-50-免疫在线蚂蚁淘旗下平台

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商品详细寿命/PathPlus™ HRH4/组胺H4受体抗体胞质域多克隆IHC LS-A6816/50µ；g（0.7 mg/ml）/LS-A6816-50

寿命/PathPlus™ HRH4/组胺H4受体抗体胞质域多克隆IHC LS-A6816/50µ；g（0.7 mg/ml）/LS-A6816-50

商品编号： LS-A6816-50

品牌： lsbio

市场价： ¥8500.00

美元价： 5100.00

产地：美国(厂家直采)

公司：

产品分类：抗猫

公司分类： Anti_Cat

联系Q Q： 3392242852

电话号码： 4000-520-616

电子邮箱： info@ebiomall.com

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商品介绍

Description

HRH4(HistaminereceptorH4)isaubiquitousmessengermoleculereleasedfrommastcells,enterochromaffin-likecells,andneurons.Itsvariousactionsaremediatedbyafamilyofhistaminereceptors,whichareasubsetoftheG-proteincoupledreceptorsuperfamily.Thisgeneencodesahistaminereceptorthatispredominantlyexpressedinhaematopoieticcells.HRH4isthoughttoplayaroleininflammationandallergyreponses,andcontrolsneutrophilreleasefrombonemarrow.Italsoplaysaroleindeterminingeosinophilshapechangeaswellasmastcellchemotaxisandcalciummobilization.LossofHRH4ingastriccarcinomasthroughdeletionisalsothoughttoplayaroleincancergrowth.J.Pharmacol.Exp.Ther.2003.305(3):1212–21.doi:10.1124/jpet.102.046581.PMID12626656;PLoSOne.2012;7(2):e31207,PMID:22363581

Target

HumanHRH4/HistamineH4Receptor

SeeAllHRH4/HistamineH4ReceptorAntibodies

Host

Rabbit

Reactivity

Human(testedor100%immunogensequenceidentity)

Predicted

Monkey(atleast90%immunogensequenceidentity)

Clonality

Polyclonal

Conjugations

Unconjugated.AlsoavailableconjugatedwithAP,APC,Biotin,FITC,HRP,PE.

Purification

Immunoaffinitypurified

Modifications

Unmodified

Applications

IHC
IHC-Paraffin(14µg/ml)
Applicationstestedforthebaseformofthisproductonly

PerformingIHC?SeeourcompletelineofImmunohistochemistryReagentsincludingantigenretrievalsolutions,blockingagentsABCDetectionKitsandpolymers,biotinylatedsecondaryantibodies,substratesandmore.

Immunogen

Synthetic21aminoacidpeptidefrom3rdcytoplasmicdomainofhumanHRH4/HistamineH4Receptor.PercentidentitywithotherspeciesbyBLASTanalysis:Human,Gibbon(100%);Marmoset(90%);Monkey(81%).

BlockingPeptide

LS-E29195-Liquid-50µg-$145.00ImmunizingpeptideusedtogenerateLS-A6816.Usefulforpre-absorptionandneutralizationoftheantibody'santigenbindingsite.

Epitope

CytoplasmicDomain

Specificity

HumanHRH4/HistamineH4Receptor.BLASTanalysisofthepeptideimmunogenshowednohomologywithotherhumanproteins.

Presentation

PBS,0.1%SodiumAzide

Storage

Aliquotandstoreundilutedat-20°Corbelowforupto1year.Canbestoredundilutedat4°Cforupto1month.Avoidfreeze-thawcycles.

Restrictions

Forresearchuseonly.